Project :Sequence Alignment and Substitution Matrices

Project :Sequence Alignment and Substitution Matrices

Input Specs: Allow the user to select peptide (protein, amino acid sequence) or nucleotide sequence

files in FASTA format, prompting for the FASTA format filename and sequence type (peptide versus

nucleotide). Allow the user to select a matrix of amino acid substitution scores (e.g. BLOSUM, PAM(n),

hydrophobicity) in the formats provided in zipped folder P1SubMatrices. You should also allow as input

your PAM(n) matrix files, despite the different delimiter format. Notice the amino

acid order in all matrices: A,R,N,D,C,Q,E,G,H,I,L,K,M,F,P,S,T,W,Y,V

For input nucleotide sequences, you may find the matrix [login to view URL] helpful, as it simulates the

following nucleotide substitution matrix:


A 4 -2 -2 1

C -2 4 1 -2

T -2 1 4 -2

G 1 -2 -2 4

Algorithmic Specs: Allow the user to select what kind of alignment is desired: global, local, or

semiglobal. Have the user input gap penalties. You will use the substitution matrix to perform a protein

alignment of the two amino acid sequences. Additionally, allow user to select affine alignment as one of the alignment types. If affine is selected, then the user should separately input the gap start

penalty and the gap extension penalty.

For any alignment type chosen, your algorithm must take Q(n2) time .

Output Specs: Output both your OPT matrix (in the case of affine that includes 3 matrices) and your

optimal alignment in a readable form to the console. In the case of ties, you need output only one

optimal alignment (not all ties).

What to turn in: You must turn in a single zipped file containing your source code, a Makefile if

needed for compilation, and a README file indicating how to compile/execute your program

Program must be written in C/C++,

Навыки: Программирование на C++, Программирование на С, Программирование на C#, Алгоритмы, Архитектура ПО

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О работодателе:
( 3 отзыв(-а, -ов) ) Edwardsville, United States

ID проекта: #29389730



Hi Client. I have skills like C, c++, C# and I am an expert for it. I would like to work with your project at fulltime and also can make your project perfectly. Please contact with me and discuss with your project.

$50 USD за 7 дней(-я)
(10 отзывов(-а))

3 фрилансеров(-а) готовы выполнить эту работу в среднем за $43


Hi I have read the description and can do the work.I have 8 years of experience in C,C++ and [login to view URL] me so we can discuss [login to view URL] forward to work with you. Thanks

$40 USD за 2 дней(-я)
(14 отзывов(-а))

Dear Sir. As an experienced algorithm expert, it is very interesting to me. I have been working on several data structure & algorithm projects such yours for over 7+ years. Since having programming contestant experienc Больше

$40 USD за 1 день
(9 отзывов(-а))