MacOS - Using Wine & WineBottler to Run Windows Applications (EASY) .........There are several ways to get Wine on a Mac. The official project website at WineHQ now provides official builds of Wine for Mac OS X. However, those aren’t necessarily the best option. These Wine binaries allow you to run Windows software, but don’t provide any helpful graphical tools for installing and setting up common applications, so they’re best for advanced users already familiar with Wine.
Instead, you should probably consider one of the third-party projects that take the Wine source code and build a more convenient interface on top of it, one that helps you quickly install and configure common applications. They often perform tweaks that you’d have to perform by hand if you were using the barebones Wine software. They include their own Wine software, too, so you only have to download one thing.
Third-party tools include WineBottler, PlayOnMac, and Wineskin. There’s also the free Porting Kit, which makes installing classic games easy, and the commercial CrossOver Mac, which is the only application here you have to pay for. We’ll be using WineBottler for this tutorial, as it seems like the most popular option among Mac users. It can create Mac .app bundles for Windows programs. The other third-party applications will work similarly, though some (like CrossOver and Porting Kit) may be much more streamlined for the apps they actually support—so if you’re looking to run a specific game, it may be worth checking to see if the other apps support that game for easy setup.